How does Blood Derived Growth Factors work?
Blood-Derived Growth Factors is an autologous preparation of platelets in concentrated plasma, usually containing a higher concentration of platelets than the normal range (150,000–350,000 platelets/μL). When platelet alpha-granules become activated, they release numerous growth factors (GFs) which stimulate cell proliferation, differentiation, and angiogenesis. High concentrations of GFs achieve the following effects: new hair growth, thickening of preexisting hair shafts, the proliferation of dermal papillae cells, and faster transition from telogen to anagen phase.GFs may also stimulate cellular differentiation and proliferation of perifollicular collagen, fibroblasts, and blood vessels, generating a thicker epithelium that increases the hair cross-section. GFs stimulate the growth of existing miniaturized hair follicles.