Is Biote(R) Hormone Replacement Therapy risky for Women?

On the contrary…

When women consider hormone replacement therapy the looming question is about the risks, especially of breast cancer, strokes and heart attacks. On review, women are the most protected during their 30’s when they have the highest hormone levels. It is only after menopause that women have increased risk of stroke, heart attack and breast cancer. Data suggests that it is hormone imbalances that contribute to breast cancer. We know that, most breast cancers occur after menopause; precisely at the time when the ovaries stop producing the normal balance of hormones.

Biote(R) Hormone Replacement Therapy Risky for Women?

The science of Breast Cancer and Hormone decline explained –

First, progesterone, which prevents breast cell division, declines from the late 30’s. Second, approximately 10 years later comes an imbalance of the estrogens. Estriol (E3) , which is breast and clot protective, decreases from 80% to 10%. Estrone (E1), which is breast and clot stimulating, goes up from 10% to 80%. The increased E1 is undesirable as E1 is converted to forms of estrogen (i.e. 16-OH E1) which are mutagenic and carcinogenic to the breast. So, restoration of protective hormone levels needs to be considered a possible preventative step against breast cancer.


But what about the  Women’s Health Initiative (WHI) study?

Large studies so far have used, synthetic, hormones (not identical to human hormones) with a ratio of estrogen weighted towards E1 like the large Women’s Health Initiative (WHI) study published in 2002, which was followed by much confusion.

Reanalysis of this study and many others has eventually led to the following three conclusions on hormone restoration in women.

  • When started early, hormones are protective on the heart and brain.
  • “Progestins” have been shown to increase clots and breast cancer in 5 trials compared with natural “progesterone” which is associated with protection.
  • Bio-identical Estradiol (E2) delivered through the skin is cardioprotective, as opposed to E1, delivered through the mouth (i.e. Oral Premarin™ used in WHI).

Did you know that Testosterone is important for both males and females?

Testosterone declines in men and women from the late 30’s onwards producing loss of desire for sex, joint and bone pain, muscle weakness, loss of confidence, moodiness, depression, anxiety, muscle loss and fat gain. Testosterone restoration not only addresses these symptoms; but studies support a protective role for testosterone against heart disease, cognitive decline and bone loss.

How to get started:

Start by calling our office at 847-686-4444 to schedule an initial consultation with Dr. Malhotra. At your initial consultation Dr. Malhotra will conduct a thorough review of your past and current medical history, order required tests, evaluate your current hormone levels, symptoms and lifestyle in order to determine a course of treatment that is best for you.

Risky for Women?  |  Risky for Men?

Content reference – “Anti-Aging Medicine” – Reality or Myth? by Sangeeta Pati, MD